Guardians vs Tigers Final Score — May 21
Odds & predictions, free picks, prop bets, and injury updates



Cleveland Guardians
3
CLEG

Detroit Tigers
1

GAME PREDICTIONS
Model Picks
Total
Total O 7.5
Insights provided by the SportsGrid betting model
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Frequently Asked Questions
What are the latest odds and run line for Cleveland Guardians vs. Detroit Tigers?
The Detroit Tigers are favored by 1.5 runs on the run line (-1.5), while the Cleveland Guardians are underdogs +1.5 runs. The moneyline is Cleveland Guardians +102 and Detroit Tigers -120. The over/under is set at 7.5 runs.
What are the best bets for Cleveland Guardians vs. Detroit Tigers (run line, moneyline, total)?
The SportsGrid model's top game pick is Total O 7.5. The projected margin supports this pick.

























