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Trail Blazers vs Spurs Final Score — Apr 21

Kalshi market recap, key results, and notable props

GAME PREDICTIONS Latest News

GAME PREDICTIONS

Model Picks

Spurs

Spurs -10.5

Total

Total O 219.5

Insights provided by the SportsGrid betting model

LATEST INJURY STATUS

Trail Blazers INJURIES

Out For Season

The Trail Blazers said on Thursday (Sept. 25) that Lillard won't be back on the court for the 2025-26 season due to his achilles injury.

Spurs INJURIES

Day To Day

Wembanyama did not return to Tuesday's (Apr. 21) game 2 against Portland and has been diagnosed with a concussion and will undergo further testing Wednesday, according to Shams Charania of ESPN.

Day To Day

Barnes did not return to Tuesday's (Apr. 21) Game 2 against the Trail Blazers.

Out For Season

The Spurs announced on Wednesday (Feb. 4) that Jones Garcia underwent ankle surgery and will miss the remainder of the 2025-26 season, per Tom Orsborn of the San Antonio Express-News.

Day To Day

McLaughlin did not play on Tuesday's (Apr. 21) game against Portland.

LATEST PLAYER PROPS

No Picks

Picks CURRENTLY Unavailable

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LATEST PLAYER PROPS

Frequently Asked Questions

What are the latest odds and spread for Portland Trail Blazers vs. San Antonio Spurs?

The San Antonio Spurs are favored by 10.5 points on the spread (-10.5), while the Portland Trail Blazers are underdogs +10.5 points. The moneyline is Portland Trail Blazers +488 and San Antonio Spurs -525. The total is set at 219.5 points.

What is the injury report for the Portland Trail Blazers and San Antonio Spurs?

The latest injury report shows Damian Lillard (Out For Season – achilles) for the Portland Trail Blazers, while Victor Wembanyama (Day To Day – concussion protocol), Harrison Barnes (Day To Day – wrist), David Jones Garcia (Out For Season – ankle), Jordan McLaughlin (Day To Day – ankle) are listed for the San Antonio Spurs.

What are the best bets for Portland Trail Blazers vs. San Antonio Spurs (spread, moneyline, total)?

The SportsGrid model's top game pick is Total O 219.5. The projected margin supports this pick.