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The <a href="https://www.sportsgrid.com/nba/depth-chart/new-york-knicks-depth-chart">Los Angeles Clippers</a> have a home date with the defending NBA Champions tonight. After kicking off their four-game West Coast road trip with a win at Golden State on Monday, the <a href="https://www.sportsgrid.com/nba/depth-chart/boston-celtics-depth-chart">Boston Celtics</a> come into LA as heavy favorites. The Clippers have won four of their past five but get a massive boost in competition this evening. Tip-off is set for 10:30 p.m. ET.
Spread: Celtics -11.5 | Moneyline: Celtics -500 | Clippers +385 | Total: 218.5
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<h2>Is James Harden Playing Today?</h2>
The oft-injured <a href="https://www.sportsgrid.com/nba/players/james-harden/3125">James Harden</a> has been remarkably healthy this season, missing just two games. He comes into Wednesday night nursing a groin issue and is listed as questionable on the injury report. The Clippers are already banged up with <a href="https://www.sportsgrid.com/nba/players/norman-powell/3133">Norman Powell</a> (back) and <a href="https://www.sportsgrid.com/nba/players/kris-dunn/3138">Kris Dunn</a> (knee) ruled out. Since this is the first leg of a back-to-back for LA, they may hold Harden out and regroup for tomorrow&#8217;s meeting with the Wizards.
Dunk on the sportsbooks tonight! Grab SportsGrid&#8217;s free <a href="https://www.sportsgrid.com/nba/picks">NBA picks</a> &amp; <a href="https://www.sportsgrid.com/nba/player-props">NBA props</a>.
<h2>Clippers Opponents This Week</h2>
<table style="width: 100%; border-collapse: collapse; border-style: solid; height: 96px;">
<tbody>
<tr style="height: 24px;">
<td style="width: 25%; height: 24px;">Date</td>
<td style="width: 25%; height: 24px;">Opponent</td>
<td style="width: 25%; height: 24px;">Time</td>
</tr>
<tr style="height: 24px;">
<td style="width: 25%; height: 24px;">Thursday, Jan. 23</td>
<td style="width: 25%; height: 24px;">vs <a href="https://www.sportsgrid.com/nba/depth-chart/washington-wizards-depth-chart">Washington Wizards</a></td>
<td style="width: 25%; height: 24px;">10:30 p.m. ET</td>
</tr>
<tr>
<td style="width: 25%;">Saturday, Jan. 25</td>
<td style="width: 25%;">vs <a href="https://www.sportsgrid.com/nba/depth-chart/milwaukee-bucks-depth-chart">Milwaukee Bucks</a></td>
<td style="width: 25%;">10:30 p.m. ET</td>
</tr>
</tbody>
</table>
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L.A. hosts the defending champs in a high-stakes showdown. Boston is heavily favored after a win at Golden State on Monday. Will Harden see the court tonigh?

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